Dynamical Visualization of the Dna Sequence and Its Nucleotide Content

نویسندگان

  • Alexey Pasechnik
  • Aleksandr Mylläri
  • Tapio Salakoski
چکیده

Visual inspection can help reveal patterns that would be computationally rather difficult to reveal. We present a program to visualize a DNA sequence and its nucleotide content. The program visualizes either the whole of a given sequence, or specified fragments. It also provides facilities to compare visualizations obtained for different sequences. The program uses three different algorithms for visualizations: track-based, fractal-based and visualization based on the entropy-like parameters calculated using a sliding window. Track-based visualization considers the sequence symbol-by-symbol; the other two methods also take into account also how well nucleotides are ”mixed” in the sequence. It allows an easy revealing of the repeated patterns, segments with a low content of some nucleotides, etc. Current version of the program works under Microsoft Windows.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Single Nucleotide Polymorphisms and Association Studies: A Few Critical Points

Uncovering DNA sequence variations that correlate with phenotypic changes, e.g., diseases, is the aim of sequence variation studies. Common types sequence variations are Single nucleotide polymorphism (SNP, pronounced snip).SNPs are the third-generation molecular marker. SNP represents a DNA sequence variant of a single base pair with the minor allele occurring in more than 1% of a given popula...

متن کامل

Sequence Variations of Mitochondrial DNA Displacement-Loop in Iranian Indigenous Sheep Breeds

Mitochondrial DNA (mtDNA) has been used extensively to study population genetics because it has the unique features of maternal inheritance, a relatively fast rate of evolution and lack of recombination. A total of 82 unrelated sheep from 10 Iranian indigenous sheep breeds were investigated to determinate the maternal genetic diversity using a sequence of a 685 bp segment of the displacement lo...

متن کامل

Genetic Analysis of D-Loop Region of Mitochondrial DNA Sequence in Iranian Patients with Familial Adenomatous Polyposis (FAP): A Case-Control Study

Background and Objectives: Familial adenomatous polyposis (FAP) is an inherited disorder and a rare form of colorectal cancer. This disease appears equally in both sexes and its occurrence is more in the second or third decade of life. Mutations and alterations of the mitochondrial genome, especially the D-loop region, have been reported in various human tumors. But the exact role of these muta...

متن کامل

The Phylogeny of Calligonum and Pteropyrum (Polygonaceae) Based on Nuclear Ribosomal DNA ITS and Chloroplast trnL-F Sequences

This study represents phylogenetic analyses of two woody polygonaceous genera Calligonum and Pteropyrum using both chloroplast fragment (trnL-F) and the nuclear ribosomal internal transcribed spacer (nrDNA ITS) sequence data. All inferred phylogenies using parsimony and Bayesian methods showed that Calligonum and Pteropyrum are both monophyletic and closely related taxa. They have no affinity w...

متن کامل

معرفی گیاه دارویی دارمازو (Quercus infectoria Oliv)در کوههای زاگرس و تعیین DNA بارکدینگ آن

Background: Quercus infectoria is one of the most important medicinal plants in the Zagros mountains, which from the ancient time has been taken into consideration as a known medicinal plant. Studies have shown, this species contains a wide range of medicinal properties. In this research comprehensive introduction of this medicinal tree, places of distribution and manners of correct diagnosis ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2005